We are reinventing the fundamental science underlying the development of new medicines and their use in individual patients.

The Laboratory of Systems Pharmacology (LSP) is a research and education program in the Harvard Program in Therapeutic Science (HiTS) that advances fundamental science and develops the technology needed for accelerating the invention of new medicines and personalization of patient care.

The lab’s students, faculty and staff study the molecular causes of disease, the ways drugs exert their therapeutic and adverse effects, and the design and interpretation of clinical trials. They also use machine learning and AI to develop the molecular diagnostics needed for precision medicine. LSP research will make the development of life-saving drugs more rapid and predictable, reduce the burden of therapy, lower costs, and improve outcomes for untreatable diseases. LSP training will empower students and fellows for leadership in academic research, industry, and government service.

News, Events, & Updates

LSP Seminar | Michael J. Lee

“Understanding Mechanisms of Lethality for Common Anti-Cancer Therapies”

May 9th, 2023 | 2:30pm – 3:30pm ET

WAB 563 and Zoom

LSP in the News

“Finding Solutions for Large, Interdisciplinary Data in the Laboratory of Systems Pharmacology”

Longwood Research Data Management  | April 3, 2023

Read the Blog

LSP in the News

“Multiplexed Tissue Imaging to Reveal the Spatial Biology of Cancer”

LSP in the News

“New 3D Atlas of Colorectal Cancer Promises Improved Diagnosis, Treatment”

NIH Director’s Blog | January 31, 2023

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Benjamin Gyori selected for the DARPA ASKEM program

Read about the award