We are reinventing the fundamental science underlying the development of new medicines and their use in individual patients.
The Laboratory of Systems Pharmacology (LSP) is a research and education program in the Harvard Program in Therapeutic Science (HiTS) that advances fundamental science and develops the technology needed for accelerating the invention of new medicines and personalization of patient care.
The lab’s students, faculty and staff study the molecular causes of disease, the ways drugs exert their therapeutic and adverse effects, and the design and interpretation of clinical trials. They also use machine learning and AI to develop the molecular diagnostics needed for precision medicine. LSP research will make the development of life-saving drugs more rapid and predictable, reduce the burden of therapy, lower costs, and improve outcomes for untreatable diseases. LSP training will empower students and fellows for leadership in academic research, industry, and government service.
Explore LSP Research
News, Events, & Updates
HiTS Social Lunch
“NIH Data Management Plans”
Sarah Arena and Allison Maier
December 6, 12-1:30pm | ARM108
Seminar Series
“Analysis and Management Pipelines for Large-Scale Neuroscience Imaging and Electrophysiology Data”
Christopher D Harvey, Ph.D. | Professor of Neurobiology, Harvard Medical School
November 15, 1-2pm | Goldenson 122
Watch Previous Data to Discovery Seminars
LSP in the News
“A New Tool for Diagnosing Cancer”
Catherine Caruso | June 22, 2023
Twitter @HiTSatHarvard
Congrats to CRS Fellow @ryanpknox on their new piece in @JAMAHealthForum investigating the outcomes of the 340B Drug Pricing Program on the American #healthcaresystem.
@AmeetSarpatwari @akesselheim @wbfeldman
#drugpricing #340B
2D & 3D multiplexed subcellular profiling of nuclear instability in cancer https://www.biorxiv.org/content/10.1101/2023.11.07.566063v1: Our pre-print on nuclear envelope rupture in cancer - tools to map NE rupture and GBM cell state and lineage in tissues; + high-res 3D tissue imaging. Congrats Shannon Coy + Team.
🍂The more friends, the merrier!
This year, we'll all come together for the Longwood Postdoc Association's Friendsgiving dinner on November 17th from 5-8pm at the Hale building.🦃.
Bring your favorite dessert and compete in our scrumptious 'Best Dessert' contest!🍰🍁
📰 November News Announcement: https://mailchi.mp/harvard/rdm-news-1123
So much 🆓 data skills training this month!
1⃣ RDM Seminars: http://bit.ly/RDM-Seminars
2⃣ @TheDMPTool Workshop @HMSCountway
3⃣ Metadata Webinar with @dataverseorg
4⃣@HiTSatHarvard Data to Discovery Seminar
... and more! 🥧
Excited to share our new manuscript titled, "Quality Control for Single Cell Analysis of High-plex Tissue Profiles using CyLinter", out now on bioRxiv (https://doi.org/10.1101/2023.11.01.565120). Details on this open-source software program can be found at https://labsyspharm.github.io/cylinter/.