We are reinventing the fundamental science underlying the development of new medicines and their use in individual patients.
The Laboratory of Systems Pharmacology (LSP) is a research and education program in the Harvard Program in Therapeutic Science (HiTS) that advances fundamental science and develops technology needed to accelerate the invention of new medicines and the personalization of patient care.
The lab’s students, faculty and staff study the molecular causes of disease, the ways drugs exert their therapeutic and adverse effects, and the design and interpretation of clinical trials. They also use machine learning and AI to develop the molecular diagnostics needed for precision medicine. LSP research will make the development of life-saving drugs more rapid and predictable, reduce the burden of therapy, lower costs, and improve outcomes for untreatable diseases. LSP training will empower students and fellows for leadership in academic research, industry, and government service.
Explore LSP Research
News, Events, & Updates
LSP Seminar | Anne Carpenter, Ph.D
“Image Information for Functional Genomics and Drug Discovery”
February 1st, 2pm – 3pm ET
WAB 563 and Zoom
Benjamin Gyori selected for the DARPA ASKEM program
Twitter @HiTSatHarvard
An energy-based, mechanistic model of MAPK #signalling describing the network rewiring events responsible for adaptive & genetic #drugresistance in #melanoma ➡️ http://bit.ly/3jcpVXN P Sorger @fabfrohlich @harvardmed
Researchers are building detailed 2D and 3D maps of colorectal cancer to better understand the dynamics of the disease http://hvrd.me/42Ph50Mvlg7
Thrilled to shared our paper "Multiplexed 3D atlas of state transitions and immune interaction in colorectal cancer" https://www.sciencedirect.com/science/article/pii/S0092867422015719
Please join us for a special edition of the #Regsci forum, featuring lightning talks from CRS Fellows. This is a great opportunity to learn about their amazing research! RSVP http://bit.ly/3ZYDBqf